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Most of us have only used high-THC cannabis strains known for their “munchy” effect. 

For some cannabis consumers, this appetite stimulation effect found in high THC strains is exactly what they need, especially patients who are dealing with the side effects of chemotherapy, cancer, depression, and other disorders where appetite stimulation can be life-changing. 

But for others, especially people who are struggling with obesity, diabetes, and weight or eating issues, the appetite stimulation in cannabis has not been their friend. 

If you fall into the latter category, say hello to THCV, your new best friend. 

What is THCV?

Let’s starts with a quick rundown of cannabinoid basics. 

Cannabis doesn’t directly make the cannabinoids that we are most familiar with, THC and CBD. 

These cannabinoids are produced by the metabolism of the plant into the form of cannabinoid acids. The most common types of acidic cannabinoids found in a typical cannabis plant are THCA, CBDA, CBGA, and CBCA. 

These acid cannabinoids can be converted to their neutral counterparts by decarboxylation (heat), the influence of light or prolonged storage to form THC, CBD, CBG, and CBC. 

The easiest way to wrap your head around this is to use the metaphor of the family chain. 

For example:

THCA is the granddaddy 

THC is the big daddy

THCV is the grandbaby 

THCv (Tetrahydrocannabivarin) is a minor cannabinoid found in only some strains of cannabis. For example, THCV is high in the popular African landrace strain Durban Poison, and newer strains like Pineapple Purps and Doug’s Varin. As well as high CBD strains like ACDC and Harlequin.

The only structural difference between THCV and THC is the presence of a propyl (3 carbon) group, rather than a pentyl (5 carbon) group, on the molecule. In Science, this is called an analog, which means it similar to THC, but also very different. 

Though this variation may seem subtle, it causes THCV to produce very different effects than THC. These effects include a reduction in panic attacks, suppression of appetite, and the promotion of bone growth, to name a few.

Does THCV get you high?

Big daddy THC activates the CB1 receptors in your brain, providing the intoxicating high. Whereas grandbaby THCV seems to affect the CB1 receptor oppositely. 

The limited science we have at this point is showing that at relatively low doses, THCV appears to inhibit some effects of THC while enhancing others. It counters the psychoactive effects of THC, as well as inhibiting THC induced heart rate increase and suppresses the ability to panic.

However, at relatively high doses, THCV may start to activate CB1 receptors, as THC does. According to Steep Hill Labs, “THCV is more strongly psychoactive than THC, but only has about half the duration of THC.”

For now, what we know is that the “high” associated with THCV is determined by the amount of THCV in a strain. 

Here’s what the science is showing THCV does: 

THCV is an appetite suppressant. It is a new potential treatment for obesity-associated glucose intolerance. 

THVC is being used to treat patients suffering from “metabolic syndrome”. This is where diabetes, high blood pressure, and obesity combine to increase the risk of heart disease and stroke.

THCV may protect pancreatic islet cells. THCV has been patented by GW Pharmaceutics for the protection of the pancreatic islet cells which maintain insulin production at levels that can substantially control or improve control of blood glucose levels in a patient.

THCV may help with diabetes. Research shows THCV has anti-diabetic effects like regulating blood sugar levels and reducing insulin resistance. Not only has recent science shown THCV to be involved in appetite suppression, regulating blood sugar levels, glucose appetite, and supporting metabolism, it also is showing promising results in the treatment of these other disorders.

Not only is THCV being tested for its ability to suppress appetite, and our support metabolism, it also is showing promising results in the treatment of other disorders.

THCV reduces or even blocks panic attacks. This makes it a very effective treatment in the management of PTSD, anxiety, and stress. 

THCV has a promising profile for delaying the progression of Parkinson’s Disease. As well as helping with Parkinson’s symptoms, like tremors due to its antioxidant properties, and ability to activate CB2 but to block CB1receptors. It is also showing that it helps with Parkinson’s symptoms, like tremors, due to its antioxidant properties, due to its ability to activate CB2 receptors and block CB1 receptors.

THCV stimulates bone growth. Because it promotes the growth of new bone cells, THCV is being looked at for osteoporosis and other bone-related conditions.

THCV is showing promising results as an anti-inflammatory. THCV has therapeutic potential both as an anti‐inflammatory agent and for the relief of neuropathic pain.

 Are you starting to feel the love of THCV? Join the crowd!

For now, High THCV strains may be hard to find. 

Luckily, the promising research on this little molecule has stimulated cannabis cultivators to breed new strains high in THCV.

K.W.Y.C KNOW WHAT YOU CONSUME

Our comprehensive guide will help you understand what to choose for your specific needs.

LOOK WHAT’S FRESH AT PINEAPPLE EXPRESS 

THC Premium Label Cannabis Oil Vape Kit’s

Indica 

EFFECTS: You can expect a mellow, laid back feeling. Perfect for relaxing with a movie or as a nightcap before bed.

MEDICAL:  Can decrease nausea, acute pain. Can also be great for muscle relaxation and insomnia

Sativa 

EFFECTS: Physical activity, social gatherings, and creative projects. Can also increase focus and creativity. Great for daytime use.

MEDICAL: Can be helpful for decreasing nausea, acute pain. Also can help with decreasing anxiety and depression

Hybrid 

EFFECTS:  This is a well-balanced mixture providing the best of both worlds: Energizing and uplifting while simultaneously relaxing and sedative.

MEDICAL:  Can help manage pain, anxiety, depression. Can also be helpful in mitigating insomnia, nausea, and lack of appetite